BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL — image 1 of 4

Product details

BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2424-500

Price for BNCB2424-500

Size / count 1x 500 µL

About this product

BOB-1 is a transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2, boosting the promoter activity of those complexes. It is essential for the response of B-cells to antigens, required for the formation of germinal centers, and regilates IL-6 expression. BOB-1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB-1. Conversely, only some cases of classical Hodgkin lymphoma show BOB-1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB-1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2424-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BOB-1; B-cell-specific coactivator OBF-1; OCT-binding factor 1; POU domain class 2-associating factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: POU2AF1
Gene ID: 5450
NCBI Gene ID: 654525
UniProt: Q16633
Swiss Prot: Q16633
Host: Mouse
Species Reactivity: Human
Reactivity: BOB.1
Immunogen: Recombinant human BOB1 (POU2AF1) protein fragment (around aa 148-255) (exact sequence is proprietary)
Target Antigen: BOB.1
Clonality: Monoclonal
Clone: BOB1/2424
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Immunology
Positive Control: Ramos cells. Spleen or Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL?

The catalog number for BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL is BNCB2424-500.

What sizes are available for BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL?

BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL in stock?

BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL?

BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL?

The safety data sheet for BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100a00/msds/bncb2424-500.pdf.

What is BOB.1 (B-Cell Marker) (BOB1/2424), Biotin conjugate, 0.1mg/mL used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.