Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1951-500

Price for BNCB1951-500

Size / count 1x 500 µL

About this product

Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1951-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Bcl-6; B-Cell Lymphoma 6 Protein; B-cell lymphoma 5 protein; Zinc Finger Protein 51; zinc finger transcription factor BCL6S; BCL6 Transcription Repressor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: BCL6
Gene ID: 604
NCBI Gene ID: 478588
UniProt: P41182
Swiss Prot: P41182
Host: Rabbit
Species Reactivity: Human
Reactivity: Bcl-6
Immunogen: Recombinant human bcl-6 protein fragment (around aa 256-389) (Exact sequence is proprietary)
Target Antigen: Bcl-6
Clonality: Monoclonal
Clone: BCL6/1951R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Apoptosis, Cancer, Immunology, Transcription factor
Positive Control: Raji or Ramos cells. Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 95 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL?

The catalog number for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL is BNCB1951-500.

What sizes are available for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL?

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL in stock?

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL?

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), Biotin conjugate, 0.1mg/mL used for?

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.