SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL — image 1 of 4

Product details

SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2540-500

Price for BNCB2540-500

Size / count 1x 500 µL

About this product

SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, cell survival, and metastasis. Gene expression profiling has uncovered SOX4 with upregulated activity during TGF-β -induced epithelial-mesenchymal transition (EMT) in normal and cancerous breast epithelial cells. SOX4 is indispensable for EMT and cell survival in vitro and for primary tumor growth and metastasis in vivo. SOX4 is identified as a master regulator of EMT by governing the expression of the epigenetic modifier Ezh2.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2540-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: SOX; SRY (sex determining region Y) box 4; SRY box containing gene 4; SRY related HMG box gene 4; Transcription factor SOX-4
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SOX4
Gene ID: 6659
NCBI Gene ID: 643910
UniProt: Q06945
Swiss Prot: Q06945
Host: Mouse
Species Reactivity: Human
Reactivity: SOX4
Immunogen: Recombinant full-length human SOX4 protein
Target Antigen: SOX4
Clonality: Monoclonal
Clone: SOX4/2540
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Developmental biology, Transcription factors
Positive Control: Breast or Colon Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 47 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL?

The catalog number for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL is BNCB2540-500.

What sizes are available for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL?

SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL in stock?

SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL?

SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL?

The safety data sheet for SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is SOX4 (Master Regulator of Epithelial-Mesenchymal Transition) (SOX4/2540), Biotin conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.