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Product details

P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1924-500

Price for BNCB1924-500

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Size / count 1x 500 µL

About this product

The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1924-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Antigen NY-CO-13, BCC7, Cellular Tumor Antigen p53, LFS1, TP53, Transformation Related Protein 53 (TRP53), Tumor Protein p53, Tumor Suppressor p53
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TP53
Gene ID
7157
NCBI Gene ID
654481
UniProt
P04637
Swiss Prot
P04637
Host
Mouse
Species Reactivity
Human
Reactivity
P53 Tumor Suppressor Protein
Immunogen
Recombinant full-length human TP53 protein
Target Antigen
p53 Tumor Suppressor Protein
Clonality
Monoclonal
Clone
PCRP-TP53-2A10
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Apoptosis, Tumor suppressors
Positive Control
HeLa cells. Colorectal or Ovarian Carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
53 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL?

The catalog number for P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL is BNCB1924-500.

What sizes are available for P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL?

P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL in stock?

P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL?

P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL?

The safety data sheet for P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is P53 Tumor Suppressor Protein (PCRP-TP53-2A10), Biotin conjugate, 0.1mg/mL used for?

The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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