EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL

Catalog number BNC743074-100

Price for BNC743074-100

Size / count 1x 100 µL

About this product

This antibody recognises human prolyl hydroxylase 2 (PHD2), a 46 kDa enzyme expressed abundantly in all tissues with the highest expression in testis. Hypoxia inducible factor-1 (HIF-1) is a transcriptional complex, consisting of an alpha and beta subunit, which plays a key role in coordinating the cellular response to hypoxia. During normal oxygen conditions, the alpha subunit of HIF-1 is rapidly degraded, however when hypoxia occurs this degradation is suppressed and HIF-1 activates the transcription of various genes important for survival and adaptation to hypoxia. Prolyl hydroxylase 2 catalyses the hydroxylation of specific prolyl residues within the HIF-1 alpha subunit, thereby targeting this subunit for degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC743074-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Chromosome 1 Open Reading Frame 12 (C1ORF12) ; DKFZp761F179; ECYT3; Egl 9 family hypoxia inducible factor 1; Egl nine homolog 1; Egln1; HIF Prolyl Hydroxylase 2 (HIF PH2) ; HIFPH2; HPH2; Hypoxia inducible factor prolyl hydroxylase 2; ORF13; P4H2; PhD2; PNAS 118; PNAS 137; Prolyl hydroxylase domain-containing protein 2; SM20; Zinc finger MYND domain containing protein 6 (ZMYND6)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: EGLN1
Gene ID: 54583
NCBI Gene ID: 444450
UniProt: Q9GZT9
Swiss Prot: Q9GZT9
Host: Mouse
Species Reactivity: Human
Reactivity: EGLN1|PHD2
Immunogen: Residues 1-24 of PHD2
Target Antigen: EGLN1 | PHD2
Clonality: Monoclonal
Clone: 366G/76/3
Type: Primary
Source: Animal
Origin: Animal
Positive Control: MCF7 cells. Brain or adrenal gland.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 46 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL?

The catalog number for EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL is BNC743074-100.

What sizes are available for EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL?

EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL in stock?

EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL?

EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL?

The safety data sheet for EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is EGLN1 / PHD2 (366G/76/3), CF740 conjugate, 0.1mg/mL used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.