Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL

Catalog number BNC742891-100

Price for BNC742891-100

Size / count 1x 100 µL

About this product

The complement component proteins, C2, C3, C4 and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. C3d is a terminal degradation product of C3 that plays an important role in modulation of the adaptive immune response through the interaction with complement receptor type 2 (CR2) . CR2 is important in the switched-isotype, high-affinity and memory humoral immune responses to T-dependent foreign antigens, as well as in the development of the natural antibody repertoire. This pH- and ionic strength-dependent association of C3d with CR2 represents a link between innate and adaptive immunity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742891-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Acylation stimulating protein cleavage product; AHUS5; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement component C3; CPAMD1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: C3
Gene ID: 718
NCBI Gene ID: 529053
UniProt: P01024
Swiss Prot: P01024
Host: Mouse
Species Reactivity: Human
Reactivity: Complement 3d
Immunogen: Recombinant full-length human Complement C3 protein
Target Antigen: Complement 3d
Clonality: Monoclonal
Clone: C3D/2891
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Human kidney or rejected renal transplant tissue.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 35 kDa (predicted)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL?

The catalog number for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL is BNC742891-100.

What sizes are available for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL?

Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL in stock?

Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL?

Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Complement 3d (C3d) (Acute Humoral Rejection Marker) (C3D/2891), CF740 conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.