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Product details
Catalog number BNC743085-100
Price for BNC743085-100
Size / count 1x 100 µL
The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/3085), CF740 conjugate, 0.1mg/mL is BNC743085-100.
MSH6 (DNA Mismatch Repair Protein) (MSH6/3085), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
MSH6 (DNA Mismatch Repair Protein) (MSH6/3085), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MSH6 (DNA Mismatch Repair Protein) (MSH6/3085), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/3085), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MSH6 (DNA Mismatch Repair Protein) (MSH6/3085), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101b0e/msds/bnc743085-100.pdf.
The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacter
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
