Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL — image 1 of 4

Product details

Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL

Catalog number BNC742894-100

Price for BNC742894-100

Size / count 1x 100 µL

About this product

Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin alpha and spectrin beta are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta I (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin beta III is highly homologous to both spectrin beta I and spectrin beta II. Spectrin beta III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742894-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Beta III spectrin; SCA5; Spectrin beta chain brain 2; Spectrin beta non-erythrocytic 2; Spectrin non-erythroid beta chain 2; Spinocerebellar ataxia 5; SPTBN2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SPTBN2
Gene ID: 6712
NCBI Gene ID: 26915
UniProt: O15020
Swiss Prot: O15020
Host: Rabbit
Species Reactivity: Human
Reactivity: Spectrin Beta-III
Immunogen: Recombinant human SPTBN2 fragment (aa356-475) (exact sequence is proprietary)
Target Antigen: Spectrin Beta-III
Clonality: Recombinant Monoclonal
Clone: SPTBN2/2894R
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Cytoskeleton
Positive Control: HeLa cells. Pancreas or Liver.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 246 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL?

The catalog number for Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL is BNC742894-100.

What sizes are available for Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL?

Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL in stock?

Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL?

Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Spectrin beta III (SPTBN2) (SPTBN2/2894R), CF740 conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.