MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL

Catalog number BNC743000-100

Price for BNC743000-100

Size / count 1x 100 µL

About this product

The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC743000-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA replication licensing factor MCM6; MCM6 minichromosome maintenance deficient 6; MIS5 homolog; p105MCM
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MCM6
Gene ID: 4175
NCBI Gene ID: 444118
UniProt: Q14566
Swiss Prot: Q14566
Host: Mouse
Species Reactivity: Human
Reactivity: MCM6
Immunogen: Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary)
Target Antigen: MCM6
Clonality: Monoclonal
Clone: MCM6/3000
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human skin or squamous cell carcinoma (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 105 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL?

The catalog number for MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL is BNC743000-100.

What sizes are available for MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL in stock?

MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL?

MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL?

The safety data sheet for MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MCM6 (Proliferation Marker) (MCM6/3000), CF740 conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.