Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL

Catalog number BNC743146-100

Price for BNC743146-100

Size / count 1x 100 µL

About this product

Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase II, a serine/threonine protein kinase known to modulate the activity of other HLH transcription factors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC743146-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BHLHa17; Class A basic helix-loop-helix protein 17; OTTHUMP00000009563; OTTHUMP00000009564; SCL; STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR; Stem cell protein; T cell acute lymphocytic leukemia 1; T cell acute lymphocytic leukemia 1 protein; T cell acute lymphocytic leukemia 1 protein; T cell leukemia/lymphoma 5 protein; T-cell acute lymphocytic leukemia protein 1; T-cell leukemia/lymphoma protein 5; Tal 1 product; TAL 1 protein; TAL bHLH transcription factor 1 erythroid differentiation factor; TAL-1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TAL1
Gene ID: 6886
NCBI Gene ID: 705618
UniProt: P17542
Swiss Prot: P17542
Host: Mouse
Species Reactivity: Human
Reactivity: Tal1
Immunogen: Recombinant human full-length TAL1 protein
Target Antigen: Tal1
Clonality: Monoclonal
Clone: TAL1/3146
Type: Primary
Source: Animal
Origin: Animal
Positive Control: A549 xenograft.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 42 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL?

The catalog number for Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL is BNC743146-100.

What sizes are available for Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL?

Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL in stock?

Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL?

Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Tal1 (TAL1/3146), CF740 conjugate, 0.1mg/mL used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.