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Product details

Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL

Catalog number BNC742886-100

Price for BNC742886-100

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Size / count 1x 100 µL

About this product

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC742886-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGKC
Gene ID
3514
NCBI Gene ID
449609
UniProt
P01601; P01834
Swiss Prot
P01601 & P01834
Host
Rabbit
Species Reactivity
Human
Reactivity
IGKC|Kappa Light Chain
Immunogen
Recombinant full-length human Ig kappa chain
Target Antigen
IGKC | Kappa Light Chain
Clonality
Recombinant Monoclonal
Clone
KLC2886R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
~22.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL?

The catalog number for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL is BNC742886-100.

What sizes are available for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL?

Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL in stock?

Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL?

Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Human Kappa Light Chain / IGKC (B-Cell Marker) (KLC2886R), CF740 conjugate, 0.1mg/mL used for?

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two li

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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