MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL

Catalog number BNC742992-100

Price for BNC742992-100

Size / count 1x 100 µL

About this product

Recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3) . Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in breast, lung and salivary gland tissues. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3) . The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742992-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Intestinal mucin-3A; intestinal mucin-like; MUC3; MUC3A; MUC3B; mucin 3; intestinal; mucin 3A; cell surface associated; mucin 3A; intestinal; mucin 3B; cell surface associated
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MUC3A
Gene ID: 4584 & 57876
NCBI Gene ID: 744422 & 744530
UniProt: Q02505; Q9H195
Swiss Prot: Q02505 & Q9H195
Host: Rabbit
Species Reactivity: Human
Reactivity: MUC3
Immunogen: A synthetic peptide of 35 amino acids, SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS), which contains two of the MUC3 tandem repeats, coupled to KLH.
Target Antigen: MUC3
Clonality: Recombinant Monoclonal
Clone: MUC3/2992R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Mucins
Positive Control: LS174T cells. Human small intestine (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 1100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL?

The catalog number for MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL is BNC742992-100.

What sizes are available for MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL?

MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL in stock?

MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL?

MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MUC3 (Mucin 3) (MUC3/2992R), CF740 conjugate, 0.1mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.