Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL

Catalog number BNC743398-100

Price for BNC743398-100

Size / count 1x 100 µL

About this product

Recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC743398-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: NO38; NPM; NPM1; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Nucleophosmin (nucleolar phosphoprotein B23 numatrin) ; Nucleophosmin; Nucleophosmin/nucleoplasmin family member 1; Numatrin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NPM1
Gene ID: 4869
NCBI Gene ID: 557550
UniProt: P06748
Swiss Prot: P06748
Host: Mouse
Species Reactivity: Human
Reactivity: Nucleophosmin
Immunogen: Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Target Antigen: Nucleophosmin
Clonality: Monoclonal
Clone: NPM1/3398
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: MCF-7, HeLa or A431 cells. Skin, Colon
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 33 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL?

The catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL is BNC743398-100.

What sizes are available for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL in stock?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/3398), CF740 conjugate, 0.1mg/mL used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.