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Product details

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL

Catalog number BNC743066-100

Price for BNC743066-100

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Size / count 1x 100 µL

About this product

The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a 'high-risk' sexually-transmitted HPV that can lead to cervical, anal, vulvar, head, neck, and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification, but is lost during malignant progression. HPV16E1/E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. HPV16E1/E4 also interacts with cyclin A and Cdk2 during the G2 phase of the cell cycle, and this association may increase the efficiency with which HPV16E1/E4 is able to prevent mitotic entry. HPV16E1/E4 also associates with keratin intermediate filaments and causes the network to collapse. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC743066-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HPV-16; HPV-16 capsid; HPV16 L1; HPV16 major capsid protein L1; Human papillomavirus type 16 L1; Human papillomavirus type 16 major capsid protein L1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
Not Applicable
UniProt
Not Applicable
Swiss Prot
Not Applicable
Host
Mouse
Species Reactivity
HPV-16
Reactivity
E4|HPV16 E1
Immunogen
Recombinant human HPV16 E1/E4 fragment (aa 36-41) .
Target Antigen
E4 | HPV16 E1
Clonality
Monoclonal
Clone
HPV16 E1/E4
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
HPV-16 infected cells. Cervical tissue.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
16 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

The catalog number for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is BNC743066-100.

What sizes are available for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL in stock?

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

The safety data sheet for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e101015/msds/bnc743066-100.pdf.

What is HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL used for?

The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a 'high-risk' sexually-transmitted HPV that can lead to cervical, anal, vulvar, head, neck, and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification, but is lost during ma

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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