APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL

Catalog number BNC743076-100

Price for BNC743076-100

Size / count 1x 100 µL

About this product

Adenomatous Polyposis Coli (APC) is a protein with many cellular functions. It is a tumor suppressor and negative regulator of Wnt signaling. APC has roles in cell adhesion and cell migration. Mutations in APC are assuciated with several diseases. The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC743076-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Adenomatous Polyposis Coli; APC; CC1; Deleted in polyposis 2.5; Protein Phosphatase 1, Regulatory Subunit 46; DP2; DP3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: APC
Gene ID: 324
NCBI Gene ID: 158932
UniProt: P25054
Swiss Prot: P25054
Host: Mouse
Species Reactivity: Human
Reactivity: Adenomatous Polyposis Coli
Immunogen: Recombinant fragment of human APC protein (around aa 1-433)
Target Antigen: Adenomatous Polyposis Coli
Clonality: Monoclonal
Clone: ALi 12-28
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (published) |IHC, frozen (published) |IP (published) |WB (published)
Positive Control: COLO 320DM whole cell lysate. HCT116 cells. Tonsil, placenta, breast or colon.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 66 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1998) 95:3122-3127. (WB, IF, epitope mapping) EMBO Rep (2005) 6:184-190. (IF) BMC Cell Biol (2006) 7: 3. (IF, WB) Int J Mol Med (2008) 21:19-31. (IHC, frozen) J Biol Chem (2012) 287(34): 28552-28563. (IP, WB)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL?

The catalog number for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL is BNC743076-100.

What sizes are available for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL?

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL in stock?

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL?

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL?

The safety data sheet for APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor) (ALi 12-28), CF740 conjugate, 0.1mg/mL used for?

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.