Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL

Catalog number BNC743194-100

Price for BNC743194-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC743194-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB1; Prohibitin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PHB
Gene ID: 5245
NCBI Gene ID: 514303
UniProt: P35232
Swiss Prot: P35232
Host: Mouse
Species Reactivity: Human
Reactivity: Prohibitin
Immunogen: Recombinant human PHB protein fragment (aa167-261) (exact sequence is proprietary)
Target Antigen: Prohibitin
Clonality: Monoclonal
Clone: PHB/3194
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control: Ramos, Jurkat, HEK293, K562, HepG2, A431 or MCF-7 cells (IF). Liver, Kidney, Heart or Endometrium (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: ~30 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL?

The catalog number for Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL is BNC743194-100.

What sizes are available for Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL in stock?

Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Prohibitin (Mitochondrial Marker) (PHB/3194), CF740 conjugate, 0.1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.