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Product details

Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL

Catalog number BNC742880-100

Price for BNC742880-100

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Size / count 1x 100 µL

About this product

Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2) ; and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer's disease and Down syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC742880-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Developmentally regulated brain protein; Drebrin 1; Drebrin; Drebrin E; Drebrin E2; Drebrin1; DrebrinE
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
DBN1
Gene ID
1627
NCBI Gene ID
130316
UniProt
Q16643
Swiss Prot
Q16643
Host
Mouse
Species Reactivity
Human
Reactivity
Drebrin 1
Immunogen
Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
Target Antigen
Drebrin 1
Clonality
Monoclonal
Clone
DBN1/2880
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
120 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL?

The catalog number for Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL is BNC742880-100.

What sizes are available for Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL?

Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL in stock?

Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL?

Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Drebrin 1 (DBN1) (DBN1/2880), CF740 conjugate, 0.1mg/mL used for?

Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2) ; and an adult type (A), generated by

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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