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Product details

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL

Catalog number BNC742982-500

Price for BNC742982-500

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Size / count 1x 500 µL

About this product

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH) . GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC742982-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
GnRH receptor; GnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; GRHR; HH7; leutinizing-releasing hormone receptor; LHRHR; LRHR; luliberin receptor; luteinizing hormone releasing hormone receptor; Type I GnRH receptor
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
GNRHR and LHCGR
Gene ID
2798; 3973
NCBI Gene ID
407587 468490
UniProt
P30968; P22888
Swiss Prot
P30968; P22888
Host
Rabbit
Species Reactivity
Human
Reactivity
GnRH Receptor|LH-RH Receptor
Immunogen
Recombinant full-length human GNRHR protein
Target Antigen
GnRH Receptor | LH-RH Receptor
Clonality
Recombinant Monoclonal
Clone
GNRHR/2982R
Type
Primary
Source
Animal
Origin
Animal
Positive Control
T47D cells. Pituitary gland, ovarian or breast cancers.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
54-60 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL?

The catalog number for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL is BNC742982-500.

What sizes are available for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL?

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL in stock?

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL?

GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is GnRH-Receptor / LH-RH Receptor (GNRHR/2982R), CF740 conjugate, 0.1mg/mL used for?

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonado

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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