C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL

Catalog number BNC742966-500

Price for BNC742966-500

Size / count 1x 500 µL

About this product

Complement C1q B Chain (C1qb) is a subunit of C1q. C1q is composed of 6 polypeptide chains each of C1qa, C1qb, and C1qc. C1q is a component of the classical complement pathway, and thereby plays an important role in the immune response. Each C1q subunit contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742966-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: C1QB; Complement component 1 q subcomponent B chain; Complement component C1q B chain
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: C1QB
Gene ID: 713
NCBI Gene ID: 8986
UniProt: P02746
Swiss Prot: P02746
Host: Mouse
Species Reactivity: Human
Reactivity: C1QB|Complement C1q B-Chain
Immunogen: Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary)
Target Antigen: C1QB | Complement C1q B-Chain
Clonality: Monoclonal
Clone: C1QB/2966
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Immunology
Positive Control: Human liver, kidney or brain (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 26-29 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL?

The catalog number for C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL is BNC742966-500.

What sizes are available for C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL?

C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL in stock?

C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL?

C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL?

The safety data sheet for C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is C1QB / Complement C1q B-Chain (C1QB/2966), CF740 conjugate, 0.1mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.