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Product details

MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL

Catalog number BNC052349-100

Price for BNC052349-100

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Size / count 1x 100 µL

About this product

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) . Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC052349-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CA125; Cancer antigen 125; MUC16; Mucin16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CA125
Gene ID
94025
NCBI Gene ID
432676
UniProt
Q8WXI7
Swiss Prot
Q8WXI7
Host
Rabbit
Species Reactivity
Human
Reactivity
CA125|MUC16
Immunogen
Recombinant full-length human MUC16 protein
Target Antigen
CA125 | MUC16
Clonality
Recombinant Monoclonal
Clone
OCA125/2349R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Mucins
Positive Control
MDA-MB-468 cells. Ovarian Cancer
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
>2,000 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405M

Frequently Asked Questions

What is the catalog number for MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL?

The catalog number for MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL is BNC052349-100.

What sizes are available for MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL?

MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL in stock?

MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL?

MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL?

Estimated delivery time for MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL?

The safety data sheet for MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MUC16 / CA125 (Ovarian Carcinoma Marker) (OCA125/2349R), CF405M conjugate, 0.1mg/mL used for?

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) . Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epith

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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