HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL

Catalog number BNC743066-500

Price for BNC743066-500

Size / count 1x 500 µL

About this product

The human papilloma virus (HPV) family of DNA tumor viruses includes HPV16, a 'high-risk' sexually-transmitted HPV that can lead to cervical, anal, vulvar, head, neck, and penile cancer. The HPV16E1/E4 protein is expressed abundantly in cells supporting viral DNA amplification, but is lost during malignant progression. HPV16E1/E4 causes G2 cell cycle arrest by associating with and preventing the nuclear entry of Cdk1/cyclin B1 complexes. HPV16E1/E4 also interacts with cyclin A and Cdk2 during the G2 phase of the cell cycle, and this association may increase the efficiency with which HPV16E1/E4 is able to prevent mitotic entry. HPV16E1/E4 also associates with keratin intermediate filaments and causes the network to collapse. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC743066-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: HPV-16; HPV-16 capsid; HPV16 L1; HPV16 major capsid protein L1; Human papillomavirus type 16 L1; Human papillomavirus type 16 major capsid protein L1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: Not Applicable
UniProt: Not Applicable
Swiss Prot: Not Applicable
Host: Mouse
Species Reactivity: HPV-16
Reactivity: E4|HPV16 E1
Immunogen: Recombinant human HPV16 E1/E4 fragment (aa 36-41) .
Target Antigen: E4 | HPV16 E1
Clonality: Monoclonal
Clone: HPV16 E1/E4
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HPV-16 infected cells. Cervical tissue.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 16 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

The catalog number for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is BNC743066-500.

What sizes are available for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL in stock?

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL?

The safety data sheet for HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HPV16 E1/E4 (Human Papilloma Virus 16) (HPV16 E1/E4), CF740 conjugate, 0.1mg/mL used for?

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.