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Product details

Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL

Catalog number BNC743240-500

Price for BNC743240-500

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Size / count 1x 500 µL

About this product

Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer's disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC743240-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
9.5S alpha 1 glycoprotein; Amyloid P component serum (APCS) ; Pentaxin related; Pentraxin 2 (PTX2) ; Serum Amyloid P (SAP) ; Serum amyloid P component
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
APCS
Gene ID
325
NCBI Gene ID
507080
UniProt
P02743
Swiss Prot
P02743
Host
Mouse
Species Reactivity
Human
Reactivity
APCS|Serum Amyloid P
Immunogen
Recombinant fragment of human APCS protein (around aa 143-223) (exact sequence is proprietary)
Target Antigen
APCS | Serum Amyloid P
Clonality
Monoclonal
Clone
APCS/3240
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human endometrial carcinoma tissue (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
200 kDa (oligomeric) ; 26 kDa (non-covalently bound subunit) ; 30 kDa (glycosylated SAP subunit)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL?

The catalog number for Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL is BNC743240-500.

What sizes are available for Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL?

Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL in stock?

Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL?

Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Serum Amyloid P / APCS (APCS/3240), CF740 conjugate, 0.1mg/mL used for?

Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly establ

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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