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Product details

Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL

Catalog number BNC743001-500

Price for BNC743001-500

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Size / count 1x 500 µL

About this product

Iron (Fe) is a tightly metabolically controlled mineral and growth factor present in all living cells. Iron not bound in erythrocyte hemoglobin is transported by transferrin (Tf), the iron transport protein of vertebrate serum. The transferrin protein contains two homologous domains, each of which contain an Fe-binding site. The majority of transferrin is synthesized in the liver and secreted into the blood, but it is also produced in lower amounts in testis and brain as well as in oligodendrocytes, where transferrin is an early marker of oligodendrocyte differentiation. From the blood, transferrin is internalized by erythroblasts and reticulocytes upon binding the transferrin receptor (TfR), also designated CD71, through a system of coated pits and vesicles. After Fe release, transferrin is returned to the extracellular medium, where it can be reused. Defects in the transferrin gene results in atransferrinemia, a rare autosomal recessive disorder characterized by microcytic anemia and iron loading. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC743001-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Apotransferrin; Beta-1 metal-binding globulin; Serotransferrin; Siderophilin; TF; TFQTL1; Transferrin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TF
Gene ID
7018
NCBI Gene ID
518267
UniProt
P02787
Swiss Prot
P02787
Host
Mouse
Species Reactivity
Human
Reactivity
Transferrin
Immunogen
Recombinant fragment (around aa 311-445) of human TF protein (exact sequence is proprietary)
Target Antigen
Transferrin
Clonality
Monoclonal
Clone
TF/3001
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Jurkat, HeLa, MCF-7 or K562 cells. Human liver.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
79 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL?

The catalog number for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL is BNC743001-500.

What sizes are available for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL?

Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL in stock?

Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL?

Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Transferrin (Early Marker of Oligodendrocytes) (TF/3001), CF740 conjugate, 0.1mg/mL used for?

Iron (Fe) is a tightly metabolically controlled mineral and growth factor present in all living cells. Iron not bound in erythrocyte hemoglobin is transported by transferrin (Tf), the iron transport protein of vertebrate serum. The transferrin protein contains two homologous domains, each of which c

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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