Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL

Catalog number BNC742957-500

Price for BNC742957-500

Size / count 1x 500 µL

About this product

Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742957-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CK15; Cytokeratin 15; K1CO; Ka15; Keratin 15 basic; Keratin 15 beta; Keratin complex 1 acidic gene 15; Keratin type I cytoskeletal 15; KRT15; KRTB; KRTL15; Type I cytoskeletal 15; Type I keratin Ka15
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT15
Gene ID: 3866
NCBI Gene ID: 654570
UniProt: P19012
Swiss Prot: P19012
Host: Mouse
Species Reactivity: Human
Reactivity: Cytokeratin 15
Immunogen: Recombinant full-length human KRT15 protein
Target Antigen: Cytokeratin 15
Clonality: Monoclonal
Clone: KRT15/2957
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: HCT116, HeLa, A431 cells. Skin or Colon.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 52 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2c, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL is BNC742957-500.

What sizes are available for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL?

Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL in stock?

Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL?

Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) (KRT15/2957), CF740 conjugate, 0.1mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.