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Product details

ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL

Catalog number BNC743207-500

Price for BNC743207-500

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Size / count 1x 500 µL

About this product

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC743207-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Erb; ESR BETA; ESR2; ESRB; ESTRB; estrogen nuclear receptor beta variant a; estrogen nuclear receptor beta variant b; estrogen receptor 2 (ER beta) ; estrogen receptor beta 4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ESR2
Gene ID
2100
NCBI Gene ID
660607
UniProt
Q92731
Swiss Prot
Q92731
Host
Mouse
Species Reactivity
Human
Reactivity
ER-beta-1
Immunogen
Recombinant full-length human ESR2 protein
Target Antigen
ER-beta-1
Clonality
Monoclonal
Clone
ESR2/3207
Type
Primary
Source
Animal
Origin
Animal
Positive Control
Ovarian, breast, bladder, gastric or salivary carcinoma (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
53-59 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL?

The catalog number for ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL is BNC743207-500.

What sizes are available for ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL?

ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL in stock?

ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL?

ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL?

The safety data sheet for ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is ER-beta-1 (Estrogen Receptor beta-1) (ESR2/3207), CF740 conjugate, 0.1mg/mL used for?

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of repro

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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