Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL — image 1 of 2

Product details

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL

Catalog number BNC742883-500

Price for BNC742883-500

Size / count 1x 500 µL

About this product

DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742883-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: DNA topoisomerase I; TOP1MT; Topoisomerase I mitochondrial; Type IB Topoisomerase
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TOP1MT
Gene ID: 116447
NCBI Gene ID: 528574
UniProt: Q969P6
Swiss Prot: Q969P6
Host: Rabbit
Species Reactivity: Human
Reactivity: Topoisomerase I, Mitochondrial
Immunogen: Recombinant full-length human TOP1MT protein
Target Antigen: Topoisomerase I, Mitochondrial
Clonality: Recombinant Monoclonal
Clone: TOP1MT/2883R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cell cycle
Positive Control: A431 cells. Heart, Skeletal muscle, brain or fetal liver.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 70 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL?

The catalog number for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL is BNC742883-500.

What sizes are available for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL?

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL in stock?

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL?

Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Topoisomerase I, Mitochondrial (TOP1MT) (TOP1MT/2883R), CF740 conjugate, 0.1mg/mL used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.