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Product details

TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL

Catalog number BNC042946-500

Price for BNC042946-500

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Size / count 1x 500 µL

About this product

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC042946-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Enhancer of split groucho 1 (ESG1) ; Enhancer of split groucho-like protein 1; GRG1; TLE1; Transducin like enhancer of split 1; Transducin-like enhancer protein 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TLE1
Gene ID
7088
NCBI Gene ID
197320; 689805
UniProt
Q04724
Swiss Prot
Q04724
Host
Rabbit
Species Reactivity
Human
Reactivity
TLE1
Immunogen
Recombinant human TLE1 fragment (aa 175-338) (exact sequence is proprietary)
Target Antigen
TLE1
Clonality
Recombinant Monoclonal
Clone
TLE1/2946R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Transcription factors
Positive Control
HeLa, HepG2 or Jurkat cells. Endometrium Carcinoma or Sarcomas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
83 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL?

The catalog number for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL is BNC042946-500.

What sizes are available for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL?

TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL in stock?

TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL?

TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL?

The safety data sheet for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), CF405S conjugate, 0.1mg/mL used for?

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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