Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL — image 1 of 2

Product details

Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL

Catalog number BNC042024-500

Price for BNC042024-500

Size / count 1x 500 µL

About this product

This antibody recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042024-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ATN, CMM8, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, Oculocutaneous albinism IA, SHEP3, SK29-AB, Tumor rejection antigen AB, TYR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TYR
Gene ID: 7299
NCBI Gene ID: 503555
UniProt: P14679
Swiss Prot: P14679
Host: Rabbit
Species Reactivity: Human
Reactivity: Tyrosinase
Immunogen: Recombinant full-length human tyrosinase (TYR) protein
Target Antigen: Tyrosinase
Clonality: Recombinant Monoclonal
Clone: TYR/2024R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: SK-MEL-19, SK-MEL-30 cells or Melanoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70-80 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL?

The catalog number for Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL is BNC042024-500.

What sizes are available for Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL?

Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL in stock?

Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL?

Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Tyrosinase (Melanoma Marker) (TYR/2024R), CF405S conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.