GPN1 / XAB1 (DNA Repair & Protein Synthesis) (GPN1/2350), CF405S conjugate, 0.1mg/mL

About this product

GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC042350-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

ATP (GTP) binding protein (ATPBD1A) ; GPN-loop GTPase 1; GPN1; MBD2-interacting protein (MBDin) ; NTPBP; RNA polymerase II associated protein 4 (RPAP4) ; XPA-binding protein 1 (XAB1) GTPase

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

GPN1

Gene ID

11321

NCBI Gene ID

18259

UniProt

Q9HCN4

Swiss Prot

Q9HCN4

Host

Mouse

Species Reactivity

Human

Reactivity

GPN1|XAB1

Immunogen

Recombinant full-length human GPN1 protein

Target Antigen

GPN1 | XAB1

Clonality

Monoclonal

Clone

GPN1/2350

Type

Primary

Source

Animal

Origin

Animal

Applications

WB (verified)

Field of Research

Metabolism

Positive Control

Pancreas, Testis, Thyroid or Bladder.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

42 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF405S