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Product details

AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL

Catalog number BNC042552-500

Price for BNC042552-500

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 62 kDa, which is identified as AKT1. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKBbeta or RacPK-beta) and Akt3 (also designated PKB-gamma or thymoma viral proto-oncogene 3), which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. All members of the Akt family have a Pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-beta tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase (s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042552-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AKT1; PKB; Protein Kinase B Alpha; RAC-alpha serine/threonine-protein kinase
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: AKT1
Gene ID: 207
NCBI Gene ID: 525622
UniProt: P31749
Swiss Prot: P31749
Host: Mouse
Species Reactivity: Human
Reactivity: AKT1
Immunogen: Recombinant fragment of human AKT1 protein (around aa 85-189) (exact sequence is proprietary)
Target Antigen: AKT1
Clonality: Monoclonal
Clone: AKT1/2552
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Apoptosis, Cell cycle, Signal transduction
Positive Control: PDGF-treated NIH/3T3 cells. HeLa cell lysates. Human pancreas or cervical carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 62 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL?

The catalog number for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL is BNC042552-500.

What sizes are available for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL?

AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL in stock?

AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL?

AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL?

The safety data sheet for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e1010b1/msds/bnc042552-500.pdf.

What is AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2552), CF405S conjugate, 0.1mg/mL used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.