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Product details
Catalog number BNC041778-500
Price for BNC041778-500
Size / count 1x 500 µL
Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin α and spectrinβ are present in erythrocytes, whereas spectrin α II (also designated fodrin α ) and spectrinβ I (also designated fodrinβ ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrinβ III is highly homologous to both spectrinβ I and spectrinβ II. Spectrinβ III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Spectrin beta III (SPTBN2) (SPTBN2/1778), CF405S conjugate, 0.1mg/mL is BNC041778-500.
Spectrin beta III (SPTBN2) (SPTBN2/1778), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Spectrin beta III (SPTBN2) (SPTBN2/1778), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Spectrin beta III (SPTBN2) (SPTBN2/1778), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Spectrin beta III (SPTBN2) (SPTBN2/1778), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Spectrin beta III (SPTBN2) (SPTBN2/1778), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
