Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL

Catalog number BNC041748-500

Price for BNC041748-500

Size / count 1x 500 µL

About this product

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC041748-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: UBB
Gene ID: 7314
NCBI Gene ID: 356190; 520348
UniProt: P0G47; P0G48; P62979; P62987; P62988
Swiss Prot: P0G47; P0G48; P62979; P62987; P62988
Host: Mouse
Species Reactivity: Human
Reactivity: Ubiquitin
Immunogen: Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
Target Antigen: Ubiquitin
Clonality: Monoclonal
Clone: UBB/1748
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Ubiquitination
Positive Control: MCF-7, HeLa or Jurkat cells. Alzheimer's Brain.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 9 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2c, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL?

The catalog number for Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL is BNC041748-500.

What sizes are available for Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL in stock?

Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ubiquitin (Autophagy Marker) (UBB/1748), CF405S conjugate, 0.1mg/mL used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.