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Product details

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL

Catalog number BNC042460-500

Price for BNC042460-500

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Size / count 1x 500 µL

About this product

Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC042460-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CCNE1; Cyclin E1; G1/S-specific cyclin-E1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CCNE1
Gene ID
898
NCBI Gene ID
244723
UniProt
IDP24864
Swiss Prot
IDP24864
Host
Mouse
Species Reactivity
Human
Reactivity
Cyclin E
Immunogen
Recombinant human Cyclin E (CCNE1) protein fragment (around aa 10-176) (exact sequence is proprietary)
Target Antigen
Cyclin E
Clonality
Monoclonal
Clone
CCNE1/2460
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cell cycle
Positive Control
HeLa Cells. Breast or Colon Carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
53 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL?

The catalog number for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL is BNC042460-500.

What sizes are available for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL?

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL in stock?

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL?

Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cyclin E (G1/S-Phase Cyclin) (CCNE1/2460), CF405S conjugate, 0.1mg/mL used for?

Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory s

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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