HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL — image 1 of 4

Product details

HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL

Catalog number BNC042207-100

Price for BNC042207-100

Size / count 1x 100 µL

About this product

This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60) . Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (HSPs), more appropriately called as stress response proteins (SRPs) . hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone rGROEL/780, unlike LK2, recognizes only the mammalian (not bacterial) hsp60 and is useful in distinguishing hsp60 from mammals and bacteria.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042207-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 60kDa chaperonin, 60kDa heat shock protein mitochondrial, Chaperonin, 60-KD (CPN60), GROEL, HLD4, HSP65, HSPD1, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein, Short heat shock protein 60 Hsp60s1, Spastic paraplegia 13 (SPG13)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: HSPD1
Gene ID: 3329
NCBI Gene ID: 595053
UniProt: P10809
Swiss Prot: P10809
Host: Mouse
Species Reactivity: Chicken, Cow, Dog, Drosophila Does not react with bacteria, Hamster, Intestinal Worm, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus
Reactivity: HSP60
Immunogen: Recombinant full-length human HSP60 protein
Target Antigen: HSP60
Clonality: Recombinant Monoclonal
Clone: RGROEL/780
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Autoimmunity, Heat shock proteins, Immunology, Inflammation
Positive Control: HeLa or HepG2 cells. Synovial biopsies from patients with juvenile chronic arthritis. Synovial lining layer is strongly positive for hsp60. Breast carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 60 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL?

The catalog number for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL is BNC042207-100.

What sizes are available for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL?

HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL in stock?

HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL?

HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL?

The safety data sheet for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102bbe/msds/bnc042207-100.pdf.

What is HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), CF405S conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.