EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL — image 1 of 3

Product details

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL

Catalog number BNC042600-100

Price for BNC042600-100

Size / count 1x 100 µL

About this product

EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042600-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Erbb1 variant III; ERBB1 variant III; HER1 variant III; Proto-oncogene c-ErbB-1 variant III; Receptor Tyrosine Protein Kinase variant III; ErbB1 variant III
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: EGFR
Gene ID: 1956
NCBI Gene ID: 488293
UniProt: P00533
Swiss Prot: P00533
Host: Rabbit
Species Reactivity: Human
Reactivity: EGFRvIII
Immunogen: KLH conjugate of EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)
Target Antigen: EGFRvIII
Clonality: Recombinant Monoclonal
Clone: GFR/2600R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Signal transduction
Positive Control: A431 cells. Placenta, Breast, Colon or Bladder Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~145 kDa (vIII variant)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL?

The catalog number for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL is BNC042600-100.

What sizes are available for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL in stock?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL?

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL?

The safety data sheet for EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1019ef/msds/bnc042600-100.pdf.

What is EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), CF405S conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.