Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL

Catalog number BNC041957-100

Price for BNC041957-100

Size / count 1x 100 µL

About this product

Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC041957-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ATOD2; Epidermal Filaggrin; Filaggrin; Filaggrin precursor; Fillagrin; FLG; Profilaggrin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FLG
Gene ID: 2312
NCBI Gene ID: 654510
UniProt: P20930
Swiss Prot: P20930
Host: Rabbit
Species Reactivity: Human
Reactivity: Filaggrin
Immunogen: Recombinant human Filaggrin protein fragment (around aa 198-288) (exact sequence is proprietary)
Target Antigen: Filaggrin
Clonality: Recombinant Monoclonal
Clone: FLG/1957R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cell adhesion
Positive Control: U-251-MG cells. Skin.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 26-45 kDa (Processed) ; 350 kDa (Profilaggrin)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL?

The catalog number for Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL is BNC041957-100.

What sizes are available for Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL?

Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL in stock?

Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL?

Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Filaggrin (Keratinocyte Differentiation Marker) (FLG/1957R), CF405S conjugate, 0.1mg/mL used for?

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.