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Product details

HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL

Catalog number BNC042967-100

Price for BNC042967-100

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Size / count 1x 100 µL

About this product

This antibody reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC042967-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DP; HLA-DQ; HLA-DR
Gene ID
3115 (HLA-DP); 3117 (HLA-DQ); 3122 (HLA-DR)
NCBI Gene ID
347270 (HLA-DP); 550475 (HLA-DQ); 520048 (HLA-DR)
UniProt
P04440 (HLA-DP); P01908; P01909; P01920 (HLA-DQ); P01903 (HLA-DR)
Swiss Prot
P04440 (HLA-DP) ; P01908; P01909; P01920 (HLA-DQ) ; P01903 (HLA-DR)
Host
Rabbit
Species Reactivity
Human
Reactivity
HLA-DP/-DQ/-DR
Immunogen
Non-T, non-B human acute lymphoblastic leukemia REH6 cell line
Target Antigen
HLA-DP/-DQ/-DR
Clonality
Recombinant Monoclonal
Clone
HLA-Pan/2967R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Immunology, MHC antigens
Positive Control
Raji cells. Tonsil or lymph node
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
33-35 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL?

The catalog number for HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL is BNC042967-100.

What sizes are available for HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL?

HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL in stock?

HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL?

HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL?

The safety data sheet for HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HLA-Pan (MHC II) (HLA-Pan/2967R), CF405S conjugate, 0.1mg/mL used for?

This antibody reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting ce

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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