E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL — image 1 of 3

Product details

E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL

Catalog number BNC042208-100

Price for BNC042208-100

Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 120-80 kDa, identified as E-cadherin. Cadherins comprise a family of calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as beta-catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042208-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Arc 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD324; CDH1; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependent adhesion protein; Liver cell adhesion molecule (LCAM) ; Uvomorulin (UVO)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CDH1
Gene ID: 999
NCBI Gene ID: 461086
UniProt: P12830
Swiss Prot: P12830
Host: Rabbit
Species Reactivity: Human
Reactivity: CD324|E-Cadherin
Immunogen: Recombinant full-length human E-Cadherin protein
Target Antigen: CD324 | E-Cadherin
Clonality: Recombinant Monoclonal
Clone: CDH1/2208R
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Cell adhesion
Positive Control: MCF-7, LS174T, Raji, HT29, SK-BR3 cells. Prostate or Colon carcinomas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 120-80 kDa (Mature) ; 135 kDa (Precursor)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL?

The catalog number for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL is BNC042208-100.

What sizes are available for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL?

E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL in stock?

E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL?

E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL?

The safety data sheet for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF405S conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.