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Product details

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL

Catalog number BNC041813-100

Price for BNC041813-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC041813-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BDMF; DMSFH; DMSMFH; Epididymis luminal protein 249; HEL249; LGMBF; MeSAdo phosphorylase; Methylthioadenosine phosphorylase; MSAP; MTA phosphorylase; MTAP; MTAPase; S-methyl-5''-thioadenosine phosphorylase
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MTAP
Gene ID
4507
NCBI Gene ID
193268
UniProt
Q13126
Swiss Prot
Q13126
Host
Mouse
Species Reactivity
Human
Reactivity
MTAP
Immunogen
Recombinant human MTAP protein fragment (aa97-196) (exact sequence is proprietary)
Target Antigen
MTAP
Clonality
Monoclonal
Clone
MTAP/1813
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
DNA repair
Positive Control
HepG2, A431, HeLa, HAP1 or MCF-7 cells. Kidney.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
31 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL?

The catalog number for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL is BNC041813-100.

What sizes are available for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL in stock?

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL?

The safety data sheet for MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MTAP (Tumor Suppressor Marker) (MTAP/1813), CF405S conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding M

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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