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Product details

CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL

Catalog number BNC882083-500

Price for BNC882083-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC882083-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Activation B7-2 antigen; B lymphocyte activation antigen B72; CD28 antigen ligand 2; CD28LG2; CLS1; CTLA-4 counter-receptor B7.2; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly-58; MB7-2; TS/A-2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD86
Gene ID
942
NCBI Gene ID
171182
UniProt
P42081
Swiss Prot
P42081
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
CD86
Immunogen
Recombinant full-length human CD86 protein
Target Antigen
CD86
Clonality
Recombinant Monoclonal
Clone
RC86/1146
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Cancer immunotherapy/immune checkpoint, Immunology
Positive Control
293T or Jukat cells. Monocytes and dendritic cells, activated T, B and natural killer cells in lymph node or tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
70 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL?

The catalog number for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL is BNC882083-500.

What sizes are available for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL?

CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL in stock?

CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL?

CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL?

The safety data sheet for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD86 (Dendritic Cells Maturation Marker) (rC86/1146), CF488A conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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