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Product details

Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL

Catalog number BNC882030-500

Price for BNC882030-500

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Size / count 1x 500 µL

About this product

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complexes with many different proteins including the tumor suppressor protein APC. Defects in beta-catenin are associated with colorectal cancer, as well as many other cancer types. Beta-catenin is normally localized to the cell membrane, but can translocate to the nucleus in response to certain cell signaling. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC882030-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Beta-catenin; Catenin beta-1; Catenin (Cadherin associated protein), beta 1; CTNNB
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CTNNB1
Gene ID
1499
NCBI Gene ID
476018
UniProt
P35222
Swiss Prot
P35222
Host
Rabbit
Species Reactivity
Human
Reactivity
Beta-catenin|Catenin, Beta
Immunogen
Recombinant full-length human Î2-catenin protein
Target Antigen
Beta-catenin | Catenin, Beta
Clonality
Recombinant Monoclonal
Clone
CTNNB1/2030R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cell adhesion, Developmental biology, Signal transduction
Positive Control
HeLa or MCF-7 cells. Breast carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
92 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL?

The catalog number for Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL is BNC882030-500.

What sizes are available for Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL?

Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL in stock?

Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL?

Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Catenin, beta (CTNNB1) (CTNNB1/2030R), CF488A conjugate, 0.1mg/mL used for?

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complex

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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