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Product details

Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL

Catalog number BNC882983-500

Price for BNC882983-500

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Size / count 1x 500 µL

About this product

This MAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L) . Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H) . Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC882983-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
68kDa neurofilament protein, Light molecular weight neurofilament protein, NEFL, Neurofilament light polypeptide 68kDa, Neurofilament light polypeptide, Neurofilament protein, light chain, Neurofilament subunit NF-L, Neurofilament triplet L protein, NF-L, NF68
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NEFL
Gene ID
4747
NCBI Gene ID
521461
UniProt
P07196
Swiss Prot
P07196
Host
Rabbit
Species Reactivity
Chicken, Cow, Human, Pig, Rat
Reactivity
Neurofilament
Immunogen
Recombinant full-length human NEFL protein
Target Antigen
Neurofilament
Clonality
Recombinant Monoclonal
Clone
NEFL/2983R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton, Neuroscience
Positive Control
Brain, Neuroblastoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
68 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL?

The catalog number for Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL is BNC882983-500.

What sizes are available for Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL?

Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL in stock?

Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL?

Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Neurofilament (NF-L) (Neuronal Marker) (NEFL/2983R), CF488A conjugate, 0.1mg/mL used for?

This MAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L) . Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with m

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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