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Product details

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL

Catalog number BNC882939-500

Price for BNC882939-500

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Size / count 1x 500 µL

About this product

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous alpha and beta chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin alpha I and spectrin beta I are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta II (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC882939-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Alpha I spectrin; Elliptocytosis 2 (EL2) ; Erythrocyte alpha spectrin; Erythroid alpha-spectrin; HPP; HS3; Spectrin alpha erythrocytic 1; SPH3; SPTA1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SPTA1
Gene ID
6708
NCBI Gene ID
119825
UniProt
P02549
Swiss Prot
P02549
Host
Rabbit
Species Reactivity
Human
Reactivity
Spectrin Alpha 1
Immunogen
Recombinant fragment of human SPTA (around aa356-475) (exact sequence is proprietary)
Target Antigen
Spectrin Alpha 1
Clonality
Recombinant Monoclonal
Clone
SPTA1/2939R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cytoskeleton
Positive Control
Jurkat cells. Placenta or Tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
240 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL?

The catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL is BNC882939-500.

What sizes are available for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL in stock?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF488A conjugate, 0.1mg/mL used for?

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizer

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

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