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Product details

Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL

Catalog number BNC881968-500

Price for BNC881968-500

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Size / count 1x 500 µL

About this product

Thyroglobulin is a 660 kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881968-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
AITD3; hTG; TDH3; Tg; Tgn
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TG
Gene ID
7038
NCBI Gene ID
654591
UniProt
P01266
Swiss Prot
P01266
Host
Rabbit
Species Reactivity
Human
Reactivity
Thyroglobulin
Immunogen
Recombinant full-length human Thyroglobulin protein
Target Antigen
Thyroglobulin
Clonality
Recombinant Monoclonal
Clone
TGB/1968R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
Thyroid
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
660 kDa (Dimeric Form)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL?

The catalog number for Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL is BNC881968-500.

What sizes are available for Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL in stock?

Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Thyroglobulin (Thyroidal Cell Marker) (TGB/1968R), CF488A conjugate, 0.1mg/mL used for?

Thyroglobulin is a 660 kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic retic

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

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