Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL — image 1 of 6

Product details

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL

Catalog number BNC882168-500

Price for BNC882168-500

Size / count 1x 500 µL

About this product

Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882168-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: EMD; Emerin; Emery Dreifuss muscular dystrophy (EDMD) ; STA
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: EMD
Gene ID: 2010
NCBI Gene ID: 522823
UniProt: P50402
Swiss Prot: P50402
Host: Mouse
Species Reactivity: Human
Reactivity: Emerin
Immunogen: Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary)
Target Antigen: Emerin
Clonality: Monoclonal
Clone: EMD/2168
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Organelle markers
Positive Control: K-562, HeLa or Jurkat cells. Kidney or Skin
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 37 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL?

The catalog number for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL is BNC882168-500.

What sizes are available for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL in stock?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2168), CF488A conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.