CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) (ITGAE/2474), CF488A conjugate, 0.1mg/mL

About this product

CD103 is alpha E integrin, belonging to a small beta-7 integrin subfamily. It is primarily expressed in intraepithelial lymphocytes. Together with beta 7 integrin, it is the cell surface receptor for E-cadherin, where it mediates cell adhesion. CD103 is expressed on more than 95% of intraepithelial CD8 cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC882474-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

CD103; Integrin alpha E; Integrin subunit alpha E

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ITGAE

Gene ID

3682

NCBI Gene ID

513867

UniProt

P38570

Swiss Prot

P38570

Host

Mouse

Species Reactivity

Human

Reactivity

CD103|Integrin alpha E

Immunogen

Recombinant human ITGAE protein fragment (exact sequence is proprietary)

Target Antigen

CD103 | Integrin alpha E

Clonality

Monoclonal

Clone

ITGAE/2474

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Field of Research

Cancer, Immunology

Positive Control

Tonsil, Colon or Stomach

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

150 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG2b, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF488A