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Product details

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL

Catalog number BNC881810-500

Price for BNC881810-500

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Size / count 1x 500 µL

About this product

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous α andÎ2 chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin α I and spectrinÎ2 I are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrinÎ2 II (also designated fodrinÎ2) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881810-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Alpha I spectrin; Elliptocytosis 2 (EL2) ; Erythrocyte alpha spectrin; Erythroid alpha-spectrin; HPP; HS3; Spectrin alpha erythrocytic 1; SPH3; SPTA1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SPTA1
Gene ID
6708
NCBI Gene ID
119825
UniProt
P02549
Swiss Prot
P02549
Host
Mouse
Species Reactivity
Human
Reactivity
Spectrin Alpha 1
Immunogen
Recombinant human SPTA fragment (around aa356-475) (exact sequence is proprietary)
Target Antigen
Spectrin Alpha 1
Clonality
Monoclonal
Clone
SPTA1/1810
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cytoskeleton
Positive Control
Jurkat cells. Placenta or Tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
240 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2c, kappa
Species
, BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL?

The catalog number for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL is BNC881810-500.

What sizes are available for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL in stock?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL?

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), CF488A conjugate, 0.1mg/mL used for?

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizer

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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