Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL

Catalog number BNC881748-500

Price for BNC881748-500

Size / count 1x 500 µL

About this product

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC881748-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: UBB
Gene ID: 7314
NCBI Gene ID: 356190; 520348
UniProt: P0G47; P0G48; P62979; P62987; P62988
Swiss Prot: P0G47; P0G48; P62979; P62987; P62988
Host: Mouse
Species Reactivity: Human
Reactivity: Ubiquitin
Immunogen: Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
Target Antigen: Ubiquitin
Clonality: Monoclonal
Clone: UBB/1748
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Ubiquitination
Positive Control: MCF-7, HeLa or Jurkat cells. Alzheimer's Brain.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 9 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2c, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL?

The catalog number for Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL is BNC881748-500.

What sizes are available for Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL in stock?

Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ubiquitin (Autophagy Marker) (UBB/1748), CF488A conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.