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Product details

FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL

Catalog number BNC882305-100

Price for BNC882305-100

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Size / count 1x 100 µL

About this product

The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER) -positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC882305-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Forkhead box protein A1 (FOXA1) ; Hepatocyte nuclear factor 3-alpha (HNF-3-alpha or HNF-3A or HNF3A) ; Transcription factor 3A (TCF-3A or TCF3A)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FOXA1
Gene ID
3169
NCBI Gene ID
163484
UniProt
P55317
Swiss Prot
P55317
Host
Mouse
Species Reactivity
Human, Rat
Reactivity
FOXA1|HNF3A
Immunogen
Recombinant human FOXA1 protein fragment (around aa372-472) (exact sequence is proprietary)
Target Antigen
FOXA1 | HNF3A
Clonality
Recombinant Monoclonal
Clone
RFOXA1/1515
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Endocrinology, Transcription factors
Positive Control
HepG-2 or MCF-7 cells. Liver, Pancreas, Bladder, Prostate, Colon and Lung and Breast.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
49 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL?

The catalog number for FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL is BNC882305-100.

What sizes are available for FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL?

FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL in stock?

FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL?

FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL?

The safety data sheet for FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1018b8/msds/bnc882305-100.pdf.

What is FOXA1 / HNF3A (rFOXA1/1515), CF488A conjugate, 0.1mg/mL used for?

The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the h

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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