CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL — image 1 of 2

Product details

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL

Catalog number BNC882290-100

Price for BNC882290-100

Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP) -activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882290-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7) ; cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CFTR
Gene ID: 1080
NCBI Gene ID: 489786, 621460, 661104
UniProt: P13569
Swiss Prot: P13569
Host: Rabbit
Species Reactivity: Human, Mouse
Reactivity: CFTR
Immunogen: Recombinant full-length human CFTR protein
Target Antigen: CFTR
Clonality: Recombinant Monoclonal
Clone: CFTR/2290R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Ion channels
Positive Control: MOLT-4 cells. Pancreas, Kidney or Placenta.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 165-170 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL?

The catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL is BNC882290-100.

What sizes are available for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL in stock?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL?

The safety data sheet for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101f24/msds/bnc882290-100.pdf.

What is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/2290R), CF488A conjugate, 0.1mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.